Publications:

2002

  • Musatov A, Robinson NC. (2002) Cholate-induced dimerization of detergent- or phospholipid-solubilized bovine cytochrome C oxidase. Biochem. 41(13):4371-6.

  • Fan JY, Gordon F, Luger K, Hansen JC, Tremethick DJ. (2002) The essential histone variant H2A.Z regulates the equilibrium between different chromatin conformational states. Nat Struct Biol. 9(14):316.

  • Anderson S, Schirf V, McAlister-Henn L. (2002) Effect of AMP on mRNA binding by Yeast NAD+-Specific Isocitrate Dehydrogenase. Biochem 41(22), 7065-7073.

    2001

  • Lambert LJ, Schirf V, Demeler B, Cademe M and Werner MH. (2001) Flipping a genetic switch by subunit exchange. EMBO J. 20(24)7149-7159.

    2000

  • Musatov A, Orgeta-Lopez J, Robinson NC (2000) Detergent-Solubilized Bovine Cytochrome c Oxicase: Dimerization Depends on the Amphiphilic Environment. Biochem, 39:12996-13004.

  • Demeler B, Behlke J, Ristau O. (2000) Molecular parameters from sedimentation velocity experiments: whole boundary fitting using approximate and numerical solutions of Lamm equation. Methods Enzymology: Numerical Computer Methods, Part C, eds. L. Brand and M.J. Johnson. 321:38-66.

  • Carruthers, L.M., Schirf, V.R., Demeler, B., and Hansen, J.C. (2000) Sedimentation Velocity Analysis of Macromolecular Assemblies. Methods in Enzymology: Numerical Computer Methods, Part C, eds. L. Brand and M.J. Johnson. 321:66-80.

  • Keyhani, N. O., Rodgers, M., Demeler, B., Hansen, J., & Roseman, S. (2000). Characterization and Interaction of the IIAChb and IIBChb Proteins of the Escherichia coli N,N'-Diacetylchitobiose Phosphotransferase System by Analytical Sedimentation:Formation of a Model Phosphotransfer Transition State Complex. J.Biol.Chem.,275(42):33110-5.

  • Leslie T. Hall, Raylene J. Sanchez, Stephen P. Holloway, Haining Zhu, Jennifer E. Stine, Thomas J. Lyons, Borries Demeler, Virgil Schirf, Jeffrey C. Hansen, Aram M. Nersissian, Joan Selverstone Valentine and P. John Hart. 2000. X-ray crystallographic and analytical ultracentrifugation analysis of truncated and full-length yeast copper caperones for SOD (LYS7): A dimer-dimer model of LYS7-SOD Association and Copper Delivery. Biochemistry 39:3611-3623.

    • 1999

  • James L. Cole and Jeffey C. Hansen. (1999) Analytical ultracentrifugation as a contemporary biomolecular research tool. J. Biomolecular Tech. 10(4):163-176.

  • Musatov A, Ortega-Lopez J, Demeler B, Osborne JP, Gennis RB, Robinson NC. (1999) Detergent-solubilized Escherichia coli cytochrome bo3 ubiquinol oxidase: a monomeric, not a dimeric complex. FEBS Lett 457(1):153-6.

  • Ingram S.W., Stratemann, S.A., Barnes, L.D. (1999) Schizosaccharomyces pombe Aps1, a diadenosine 5',5' "-P1, P6-hexaphosphate hydrolase that is a member of the nudix (MutT) family of hydrolases: Cloning of the gene and characterization of the purified enzyme. Biochemistry 38(12):3649-3655.

  • Logie, C., Tse, C., Hansen, J.C., and Peterson, C.L. (1999) The Core Histone N-terminal Domains are Required for Multiple Rounds of Catalytic Remodeling by the SWI/SNF and RSC Complexes. Biochemistry 38, 2514-2522.

  • Hansen, J.C. and Turgeon, C. (1999) Analytical Ultracentrifugation of Chromatin. Meth. Mol. Biol.: Chromatin Protocols, ed. P. Becker:119:127-41..

  • Peter Schuck and Borries Demeler (1999). Direct Sedimentation Boundary Analysis of Interference Optical Data in Analytical Ultracentrifugation. Biophysical Journal 76 2288-2296

  • James M. Bullard, Ying-Chun Cai, Borries Demeler and Linda L. Spremulli (1999). Expression and Characterization of a Human Mitochondrial Phenylalanyl-tRNA Synthetase. Journal of Molecular Biology 288.4 567-577

  • Brazil, B. T., Ashley M. Buckle, B. Demeler, Alan R. Fersht, and Paul M. Horowitz. (1999) The Binding of 4,4'-bis(1-anilino-8-naphtalenesulfonic Acid) to the GroEL Apical Domain Fragment is Cooperative and Induces the Formation of a Folding Intermediate with Increased Hydrophobic Surface Exposure (in press)
    1998

  • Robinson N et al. (1998) Analysis of Detergent Solubilized Membrane Proteins in the Analytical Ultracentrifuge. ChemTracts: Biochem. Molec. Biol. 960-968.

  • Borries Demeler and Hashim Saber. Determination of Molecular Parameters by Fitting Sedimentation Data to Finite Element Solutions of the Lamm Equation. Biophysical Journal (1998) 74 (1) 444-54

  • Anant, J. S., Desnoyers, L., Machius, M., Demeler, B., Hansen, J. C., Westover, K. D., Deisenhofer, J., Seabra, M. C., Mechanism of Rab Geranylgeranylation: Formation of the Catalytic Ternary Complex, (1998). Biochemistry 37 (36) 12559-12568.

  • Rich, R. L., B. Demeler, K. Ashby, A. Höök, J. W. Petrich, C. Deivanayagam, S. V. L. Narayana, J. M. Patti, and M. Höök. Domain structure of the Staphylococcus aureus collagen adhesin. Biochemistry. 37 (44) 15423-33

  • Tse, C., Ruiz-Garcia, A.B, Georgieva, E.I., Sendra, R., and Hansen, J.C. (1998) Gcn5p, a Transcription-Related Histone Acetyltransferase, Acetylates Nucleosomes and Folded Nucleosomal Arrays in the Absence of Other Protein Subunits J. Biol. Chem. 273, 32388-32392.

  • Carruthers, L.M., Bednar, J., Woodcock, C. L. and Hansen, J.C. (1998) Linker Histones Stabilize the Intrinsic Salt-dependent Folding of Nucleosomal Arrays: Mechanistic Ramifications for Higher Order Chromatin Folding. Biochemistry 37, 14776-14787.

  • Tse, C., Sera, T., Wolffe, A. P., and Hansen, J.C. (1998) Acetylation-induced Decondensation of Nucleosomal Arrays Dramatically Facilitates Transcription by RNA Polymerase III. Mol. Cell. Biol. 18, 4629-4638.

  • Bednar, J., Horowitz, R.A., Grigoryev, S.A., Carruthers, L.M., Hansen, J.C., Koster, A.J., and Woodcock, C. L. (1998) Nucleosomes, Linker DNA and Linker Histone Form a Unique Structural Motif that Directs the Higher Order Folding and Compaction of Nucleosomal Arrays. Proc. Natl. Acad. Sci. 95, 14173-14178.

  • Tse, C., Fletcher, T. M. and Hansen, J.C. (1998) Enhanced Transcription Factor Access to Arrays of H3/H4 Tetramer-DNA Complexes: Implications for Replication and Transcription. Proc. Natl. Acad. Sci. 95, 12169-12173.

  • Boris M. Gorovits, William A. McGee, Paul M. Horowitz. 1998. Rhodanese folding is controlled by the partitioning of its folding intermediates. Biochim. Biophys. Acta. 1382: 120-128.

    • 1997

  • Borries Demeler, Hashim Saber and Jeffrey C. Hansen. Identification and Interpretation of Complexity in Sedimentation Velocity Boundaries. Biophysical Journal (1997) 72, 397-407

  • Jeffrey W. Seale, John M. Chirgwin, Borries Demeler, and Paul M. Horowitz. Preformed GroES oligomers are not required as functional cochaperonins. (1997) Journal of Protein Chemistry 16 661-668

  • Pavel Martasek, Jean-Michel Camadro, C.S. Raman, Marie Christine Lecomte, Jean Pierre Le Caer, Borries Demeler, Bernard Grandchamp, Pierre Labbe. Human Coproporphyrinogen Oxidase. Biochemical Characterization of Recombinant Normal and R231W Mutated Enzymes Expressed in E. coli as Soluble, Catalytically Active Homodimers. (1997) Cellular and Molecular Biology 43, 47-58

  • Tse, C. and Hansen, J.C. (1997) Hybrid Trypsinized Nucleosomal Arrays: Identification of Multiple Functional Roles of the H2A/H2B and H3/H4 N-Termini in Chromatin Fiber Condensation. Biochemistry 36, 11381-11388.

  • Hansen J.C., Krieder, I.K., Demeler, B. and Fletcher, T. M. (1997) Analytical Ultracentrifugation and Agarose Gel Electrophoresis as Tools for Studying Chromatin Folding in Solution. Methods 12, 62-72.

  • Hansen, J.C. (1997) The Core Histone Amino-Termini: Combinatorial Interaction Domains that Link Chromatin Structure with Function. Chemtracts: Biochem. Mol. Biol. 10, 56-69.

    • 1996

  • Schwarz, P.M., Felthauser, A., Fletcher, T.M., and Hansen, J.C. (1996) Reversible Oligonucleosome Self-Association: Dependence on Divalent Cations and Core Histone Tail Domains. Biochemistry 35, 4009-4015.

  • Fletcher, T.M. and Hansen, J.C. (1996) The Nucleosomal Array: Structure/Function Relationships. Crit. Rev. Euk. Gene Exp. 6: 149-188.

    • 1995

  • Fletcher, T. M., and Hansen, J.C. (1995) Core Histone Tail Domains Mediate Oligonucleosome Folding and Nucleosomal DNA Organization Through Distinct Molecular Mechanisms. J. Biol. Chem. 270, 25359-25362.

    • 1994

  • Robert H. Behal, Michael S. DeBuysere, Borries Demeler, Jeffrey C. Hansen, and Merle S. Olson. (1994) Pyruvate Dehydrogenase Multienzyme Complex - Characterization of Assembly Intermediates by Sedimentation Velocity Analysis. Journal of Biological Chemistry 269 (50) 31372-31377

  • Fletcher, T.M., Serwer, P. and Hansen, J.C. (1994) Quantitative Analysis of Macromolecular Conformational Changes Using Agarose Gel Electrophoresis: Application to Chromatin Folding. Biochemistry 33, 10859-10863.

  • Schwarz, P.M. and Hansen, J.C. (1994) Formation and Stability of Higher Order Chromatin Structures. Contribution of the Histone Octamer. J. Biol. Chem. 269, 16284-16289.

  • Hansen, J.C. and Wolffe, A.P. (1994) A Role for Histones H2A/H2B in Chromatin Folding and Transcriptional Repression. Proc. Natl. Acad. Sci. 91, 2339-2343.

  • Fletcher, T.M., Krishnan, U., Serwer, P. and Hansen, J.C. (1994) Quantitative Agarose Gel Electrophoresis of Chromatin: Nucleosome-Dependent Changes in Charge, Shape and Deformability at Low Ionic Strength. Biochemistry 33, 2226-2233.

  • Musatov, A., and Robinson N.C. (1994) Detergent-solubilized Monomeric and Dimeric Cytochrome bc1 Isolated from Bovine Heart. Biochemistry 33, 13005-130012.

  • Mendoza, Jose A., Demeler, Borries and Paul M. Horowitz. Alterations of the quarternary Structure of CPN 60 modulates Chaperonin assisted folding; Implications for the Mechanism of Chaperonin Action. (1994) Journal of Biological Chemistry 269 (4) 2447-2451

  • Jeffrey C. Hansen, Jacob Lebowitz, and Borries Demeler. Analytical Ultracentrifugation of Complex Macromolecular Systems. Biochemistry (1994), 33, 13155-13163